Olmesartan Medoxomil+hydrochlorothiazide
About Olmesartan Medoxomil+hydrochlorothiazide
Hydrochlorothiazide+olmesartan Medoxomil belongs to a group of medications called 'anti-hypertensives' primarily used to treat high blood pressure (hypertension). High blood pressure is a chronic condition in which the force of the blood against the artery wall is high.
Hydrochlorothiazide+olmesartan Medoxomil contains Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil works by relaxing and widening the narrowed blood vessels. Hydrochlorothiazide works by removing extra water/fluid and certain electrolyte overload from the body.
In some cases, you may experience nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, dizziness, and decreased blood pressure. If the side effects are persistent, reach out to your doctor.
Do not take Hydrochlorothiazide+olmesartan Medoxomil if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.
Uses of Olmesartan Medoxomil+hydrochlorothiazide
Medicinal Benefits
- Hydrochlorothiazide+olmesartan Medoxomil is a combination medicine used to treat high blood pressure (hypertension).
- It contains Olmesartan and Hydrochlorothiazide, which work together to control blood pressure and support heart health.
- Olmesartan is an angiotensin receptor blocker (ARB) that relaxes and widens blood vessels by blocking the effects of angiotensin, allowing smoother blood flow.
- Hydrochlorothiazide is a diuretic (water pill) that removes excess water and electrolytes from the body, helping to lower blood volume and pressure.
- By reducing strain on the heart and improving blood flow, Hydrochlorothiazide+olmesartan Medoxomil helps the heart pump more efficiently.
- Long-term use helps lower the risk of heart attack, stroke, and other heart-related complications associated with high blood pressure.
- The dual action of blood vessel relaxation and fluid reduction ensures effective and sustained blood pressure control.
Directions for Use
- Hydrochlorothiazide+olmesartan Medoxomil can be taken with or without food as advised by your doctor.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Hydrochlorothiazide+olmesartan Medoxomil as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Olmesartan Medoxomil+hydrochlorothiazide
- Stuffy nose/sore throat
- Nausea
- Upset stomach
- Headache
- High level of uric acid
- Diarrhoea
- Electrolyte imbalance
- Dehydration
- Dizziness
- Decreased blood pressure
Drug Warnings
- Do not use Hydrochlorothiazide+olmesartan Medoxomil if you are pregnant, planning for pregnancy, or unable to urinate (anuria).
- If you have diabetes and are taking Hydrochlorothiazide+olmesartan Medoxomil with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor.
- Hydrochlorothiazide+olmesartan Medoxomil is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
- Hydrochlorothiazide+olmesartan Medoxomil may pass into breast milk, so before starting Hydrochlorothiazide+olmesartan Medoxomil, either you need to stop nursing, or you should not take Hydrochlorothiazide+olmesartan Medoxomil while breastfeeding.
- Please inform your doctor before surgery if you are taking Hydrochlorothiazide+olmesartan Medoxomil, as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
- Avoid potassium salt or its substitutes while using Hydrochlorothiazide+olmesartan Medoxomil to avoid any electrolyte imbalance.
- Let your doctor know if you are taking any other medicines, including supplements and herbal products.
Drug Interactions
Drug-Drug Interactions: This medicine may interact with an antidepressant (lithium), heart rhythm-controlling medicines (digoxin), blood thinner (aspirin), antidiabetic medicines (metformin, insulin), medicines used to treat erectile dysfunction (sildenafil), medicines used to lower cholesterol levels (simvastatin), immunosuppressants (cyclosporine), and other anti-hypertensive medicines (atenolol, aliskiren, enalapril, lisinopril, ramipril, metoprolol), pain killers (ibuprofen), medicines for treating stomach ulcers (carbenoxolone).
Drug-Food Interactions: Hydrochlorothiazide+olmesartan Medoxomil may interact with high-potassium-containing food and drinks. So, if you are using any of these, please tell your doctor. Also, alcohol should not be consumed while taking Hydrochlorothiazide+olmesartan Medoxomil.
Drug-Disease Interactions: Inform your doctor if you have a history of heart attack, low blood pressure, low potassium level, low electrolytes (sodium, potassium, calcium, etc.), anuria (non-passage of urine), angioedema (an allergic condition with swelling under the skin), lupus (an autoimmune disease), kidney disease, liver disease, asthma, diabetes.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.
Pregnancy
cautionHydrochlorothiazide+olmesartan Medoxomil is not recommended during pregnancy as it is a category D pregnancy drug. This medicine may cause fetal damage and can affect the unborn baby (fetus).
Breast Feeding
cautionHydrochlorothiazide+olmesartan Medoxomil is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this. Either you need to stop breastfeeding to use Hydrochlorothiazide+olmesartan Medoxomil, or you need to stop taking Hydrochlorothiazide+olmesartan Medoxomil.
Driving
unsafeDrive with caution. Hydrochlorothiazide+olmesartan Medoxomil usually causes drowsiness and affects driving ability.
Liver
cautionHydrochlorothiazide+olmesartan Medoxomil to be taken with caution, especially if you have a liver disease history. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Kidney
cautionHydrochlorothiazide+olmesartan Medoxomil to be taken with caution, especially if you have a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.
Children
cautionThe efficacy and safety of Hydrochlorothiazide+olmesartan Medoxomil have not been established in children. If prescribed, it should be strictly under medical supervision and only if the benefits outweigh the harm.
Habit Forming
Diet & Lifestyle Advise
- Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
- Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
- Use healthy cooking oils like soybean, olive, canola, and coconut oil.
- You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
- Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
- Avoid consumption of too much salt or salty food.
- Keep your weight under control with a BMI of 19.5-24.9.
- Regular physical activity or exercise, like walking, improves your blood flow.
- Avoid chronic stress, as it can raise your blood pressure.
- Spend time with your loved ones to cope with stress and practice mindfulness techniques.
- Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.
Patients Concern
Disease/Condition Glossary
Hypertension: Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and a heart attack (when the blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure.
FAQs
Hydrochlorothiazide+olmesartan Medoxomil is used to treat high blood pressure (hypertension), a chronic condition in which the force of blood against the artery wall is high.
Hydrochlorothiazide+olmesartan Medoxomil is a combination of two medicines: Olmesartan medoximil and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into the active form, i.e., olmesartan, once absorbed in the GIT (Gastrointestinal tract). It is an angiotensin receptor blocker (ARB) that blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Hydrochlorothiazide+olmesartan Medoxomil lowers the fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.
Yes, Hydrochlorothiazide+olmesartan Medoxomil can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking Hydrochlorothiazide+olmesartan Medoxomil. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
It is unlikely that Hydrochlorothiazide+olmesartan Medoxomil affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
In case you have missed a dose of Hydrochlorothiazide+olmesartan Medoxomil, you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it is time for you to take your next dose, then do not take both doses together. Take only one dose; taking a double dose of Hydrochlorothiazide+olmesartan Medoxomil will lead to low blood pressure.
Hydrochlorothiazide+olmesartan Medoxomil can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are lifelong conditions, and one should not abruptly discontinue them without discussing it with a doctor. Discontinuing Hydrochlorothiazide+olmesartan Medoxomil may lead to increased blood pressure with a high risk of heart attack and stroke in future.
No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.
Please inform your doctor before surgery if you are taking Hydrochlorothiazide+olmesartan Medoxomil, as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.
Do not use Hydrochlorothiazide+olmesartan Medoxomil if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and are taking Hydrochlorothiazide+olmesartan Medoxomil with other blood pressure-lowering pills like aliskiren, immediately stop taking both together and consult a doctor.
Hydrochlorothiazide+olmesartan Medoxomil may start to lower blood pressure within a few days to a week, but its full effect is usually reached after 2 to 8 weeks of use. Therefore, continue using Hydrochlorothiazide+olmesartan Medoxomil for the prescribed duration to treat your condition effectively.
Your doctor may recommend taking your first dose of Hydrochlorothiazide+olmesartan Medoxomil before bedtime, as it can cause dizziness. After the initial dose, you can take it at any time of day. While most people take it in the morning, the timing isn't critical—just aim to take it at the same time each day.
Dizziness is a common side effect of Hydrochlorothiazide+olmesartan Medoxomil. Avoid driving or operating machinery if you experience dizziness.
While taking Hydrochlorothiazide+olmesartan Medoxomil, it’s helpful to make lifestyle changes that can improve both your blood pressure and your overall health. Try to maintain a healthy weight, get at least 30 minutes of exercise each day, and eat a balanced diet that includes plenty of whole grains, fruits, vegetables, and low-fat dairy. Reduce your sodium and alcohol intake, and avoid smoking. To manage stress, consider mindfulness practices and stay connected with supportive friends or family. Regularly check your blood pressure, and include omega-3-rich foods in your diet. For cooking, choose healthier oils like olive, canola, soybean, or coconut oil.
Hydrochlorothiazide+olmesartan Medoxomil may cause weight gain in some people, but it's not common. This may happen because the medication can lead to fluid retention, higher sodium levels, or increased appetite. If you notice significant weight gain, it's a good idea to talk to your doctor for advice.
In rare cases, Hydrochlorothiazide+olmesartan Medoxomil may cause serious side effects like bladder pain, bloating, blurred vision, chest pain, increased urination, or unusual weight gain or loss. While not everyone experiences these side effects, if they do occur, you should consult your doctor immediately.
It's unlikely that Hydrochlorothiazide+olmesartan Medoxomil affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.
Take Hydrochlorothiazide+olmesartan Medoxomil exactly as your doctor has instructed to manage your high blood pressure (hypertension). Since this is a long-term treatment, it's important to take it regularly as prescribed. Be sure to have regular check-ups with your doctor to track your blood pressure, adjust your dosage if needed, and ensure that the medication is working well for you. By sticking to your doctor's advice and attending follow-up appointments, you can better control your blood pressure and reduce the risk of complications.
You can take Hydrochlorothiazide+olmesartan Medoxomil with or without food as advised by the doctor. Swallow it as a whole with water.
Common side effects of Hydrochlorothiazide+olmesartan Medoxomil include a stuffy nose, sore throat, nausea, upset stomach, headache, high uric acid levels, diarrhoea, electrolyte imbalances, dehydration, dizziness, and low blood pressure. These side effects typically don’t need medical attention and usually improve over time. However, if they persist or worsen, it's important to consult your doctor.
Hydrochlorothiazide+olmesartan Medoxomil is not recommended during pregnancy, as it is classified as a Category D medication. This means it may harm the foetus and could cause damage to the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor about alternative treatments.
Follow your doctor's advice and take the right amount of medicine. Be aware of side effects and take care of yourself. If you're pregnant while on treatment, inform your doctor immediately. Don't take other medications unless instructed by the doctor. Alcohol consumption should be avoided. By following these precautions, you'll benefit most from your medicine and stay safe.
Hydrochlorothiazide+olmesartan Medoxomil should be stored in a cool and dry place away from the sunlight. Keep it out of reach from children and pets.
